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Month: July 2018

Different types of Genetic mutations

Chromosomal aberrations, point mutation, deletion of nucleotides and addition of nucleotides, loss of function and gain of function are some of the examples of different type of Genetic mutations. The term mutation was coined by Hugo De Vries in 1890. Mutation is an important phenomenon in nature for the creation of variation. “Under the influence of

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Immunogenetics class 3: T cell gene rearrangement

What is T cell receptor and How T cell receptor diversity is generated? What is MHC molecule and How different gene segment for MHC is arranged?     As like B cells, T cells are also a significant cell type of immune system. Same as B cells, Even, T cell produces surface receptors which recognize

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Immunogenetics class 2: antibody diversity

How antibody diversity occurred. How different gene segment for different antibody chains are arranged.   Antigen specific antibody is produced by each type of B lymphocyte cells. It is believed that human genome contains only around 15000 to 20000 genes, than how the diversity for different antibody gene segment is originated? Some of the proposed

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