India is making progress not only in space science but also in genetic sciences and research. Our organizations, like DBT, ICMR and other Indian organizations, are constantly putting efforts into scientific research and development.
To make scientific innovation better and available for students, researchers and professionals, various databases have been developed. Here is the list of the top 8 important Indian genetic and genomics databases.
Read more: India’s Top 5 Genetic Breakthroughs of 2025.
Key Topics:
IndiGenomes:
IndiGenomes is India’s own database of genome sequencing, developed and managed by Indigen Project (now a part of GenomeIndia). It carries 55 million variants, including indels and SNPs from the Indian population.
A thousand individuals have been selected from different regions and ethnicities in India. The database is freely available. Scientists can access it for an Indian population-based study.
Database Link: IndiGenomes.
IndiGen Human Leukocyte Antigen Allelic Frequency Data:
IndiGen Human Leukocyte Antigen Allelic Frequency Data is a part of Indigenomics and uses the HLA allele data from this project. But it is a dedicated tool designed only for HLA allele polymorphisms.
It is a dedicated repository of the HLA polymorphism frequency data from India. It covers six major HLA loci – HLA-A, B, C (class I), HLA-DPB1, DQB1 and DRB1 (class II). This tool has been used for research in immunology and HLA typing.
Database link: IndiGen Human Leukocyte Antigen Allelic Frequency Data.
SAGE:
South Asian Genomes and Exomes is an Indian database repository that contains the genomic and exomic data from South Asia. The repository contains 154 million exomic variants from 1213 samples.
It has been used for allelic frequency studies, carrier and rare genetic disease testing and pharmacogenomics. The database is managed by IGIB- Institute of Genomics and Integrative Biology. Note that IGIB manages both – IndiGenomics and the Indigen HLA databases.
Database link: SAGE.
INDEX-db:
The Indian Exome Reference Database Phase I is an online repository of genomics data. It typically contains raw sequence read files. The database is managed by the National Centre for Biological Sciences.
Researchers can upload and download genomic data from here and use it for whole genome, whole exome, SNV and CNV studies.
Database link: INDEX-db.
GenTIGS:
GenTIGS- The Gene Database on Rare Genetic Disorders is a private database on rare genetic disorders developed by the TATA Institute for Genomics and Society. It contains not only Indian but global data on rare genetic conditions, including –
Causative genes, mutations, prevalence, disease description, gene ontology terms, clinical interpretation and cross-reference resources.
Researchers, clinicians and students can retrieve and analyze rare genetic disease data for studying nonsynonymous mutations, microsatellites and duplication analysis.
Database link: GenTIGS.
MitoEpigenomeKB:
Mitochondria have their own DNA. Mutations in mitochondrial DNA also result in a genetic disease. Studying mtDNA helps us understand our health and our genome in a better way.
India is also emerging in mitochondrial DNA research. We have our own database called MitoEpigenomeKB for mitochondrial DNA alteration. This database contains a small but powerful 62 datasets from 9 different studies.
This repository helps scientists understand the mitochondrial genome, mutations and associated disorders, specifically in the Indian population.
Database link: MitoEpigenomeKB.
NutrigenDB:
NutrigenDB is India’s own nutrigenomics database, managed by IGIB (Institute of Genomics and Integrative Biology), Delhi Technology University and CSRI. The database contains 404 datasets for 161 genes and 248 variations.
The database has been prepared from various peer-reviewed literature and is freely available for researchers.
Database link: NutrigenDB.
TMC-SNPdb:
TMC-SNPdb is a pilot SNPs database from India. It is open source and freely available to mine and study single-nucleotide polymorphisms. It contains 62 whole-exome sequencing data from cancer patients and 1,14,309 SNPs.
Database link: TMC-SNPdb.
Read more: 10 Indian Programs That Quietly Protect Our DNA and Genetic Health.
Wrapping up:
These are the top 8 genetic and genomics databases from India. Any student or researcher can use it for free. Prepare your research on the Indian population, use these databases and strengthen India’s scientific and genetic profile.
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