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Tag: topology

Linking Number: A Topological Feature of DNA

  Linking number is a topological property of DNA. Linking number is a sum of twists and writhes. The numbers of time one strand of DNA turned around another strand is called as a twist while inter-coiling of the double helix is termed as a writhe. In short, writhe is a number of a time

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DNA Topology class 1: Topoisomerase

Role of Topoisomerase I and Topoisomerase II in DNA topology Topoisomerase is a class of enzyme which helps in winding and unwinding of DNA. Three forms of DNA is most prevalent in nature: circular, linear and supercoiled. Circular DNA is covalently closed and does not have any interruption in between nucleotides. Circular DNA is found in

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