How to perform a Chromosome Test?
“A type of genetic test used to find out either structural, numerical or both type of chromosomal abnormalities is known as chromosome test.” Trisomy, monosomy, deletion, duplication and translocations are …
Cytogenetics
A Brief Introduction to (FISH) Fluorescence In Situ Hybridization
“By hybridizing the fluorescently labeled probe to the complementary DNA sequence, the position of DNA sequence can directly locate on a chromosome. “ The molecular techniques alike the PCR and …
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What is Philadelphia Chromosome?- BCR-ABL1 Gene Fusion and CML
“The BCR-ABL1 gene fusion occurred due to the translocation between chromosome 9 and 22 results in chronic myeloid leukemia, the truncated chromosome is called the Philadelphia chromosome.” Chromosomal abnormalities can …
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Role Of L-Glutamine In Karyotyping
The L-Glutamine is an essential amino acid and a secondary energy source required for in vitro cell culture. It is an unmatched requirement for any tissue culture experiment. Although it …
What Is The Role Of RPMI 1640 In Karyotyping?
“The RPMI 1640 is a culture medium used for the cell culture that provides all the essential nutrients to the culturing cells.” Karyotyping is a process of finding any alteration …
A Karyotyping Protocol For Peripheral Blood Lymphocyte Culture
The peripheral blood lymphocyte culture is one of the most routinely used and traditional methods for karyotyping analysis. T- lymphocyte elements of the whole blood are used for Peripheral Blood …
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