What Is shRNA (Short-hairpin RNA)?
“The shRNA is an artificial dsRNA loop or hairpin applicable in the gene silencing studies which rely on the mechanism of RNA interference.” The mechanism of shRNA action is similar […]
Small Interfering RNA- Structure, Function, Applications, Advantages and Limitations
“Small interfering RNA binds to the mRNA and performs gene silencing. Learn the concept, structure, function and applications of siRNA in this article.” The siRNA and other smaller double-stranded RNAs
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What is Single Nucleotide Polymorphism (SNP)?- The Basics
“Single Nucleotide Polymorphism is a single nucleotide alteration within a DNA sequence that produces different alleles. Explore the concept of SNPs in this article.” The human genome is mysterious. With
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Multifunctional DNA Polymerase: An Overview
Using the 3’ OH end of the primer, DNA polymerase adds nucleotides to the growing DNA strand for facilitating replication. Different types of DNA polymerases help in different steps of
An Introduction To Genome-Wide Association Study (GWAS)
The Genome-wide association study is a method used to find out common SNPs associated with complex diseases. For that, the single nucleotide variations from the whole genome are scanned and
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We Can Live Longer In Space
The length of the telomeres of the human chromosome has a significant role in the ageing process. The length of the telomeres in inversely proportional to the age of an