“The Cas9 protein is a nuclease that destroys phage DNA using the double RNA-guided DNA cleavage through DNA binding and nuclease activities.” Key points: Cas9 protein is predominantly present in …
Cas9 Protein: Structure, Function, Types and Importance Read More »
“CRISPR works magically in every sense! Every time scientists doubt something and do research, they get more than that, something new and amazing. Yet, it’s not so complex.” Do you …
How does the CRISPR CAS9 System Distinguish Self vs Nonself DNA?- 7 Proven mechanisms Read More »
“The Year 2020, was the grand time for Ataxia treatment based on the CRISPR-based technology. Three consecutive studies on Ataxia type 1, type 2 and type 3 proving the CRISPR …
tracrRNA short for Trans-active crRNA binds with the crRNA and guides the CAS protein for effective DNA cleaving. “CRISPR-CAS9 system is an integral part of the bacterial immune system and …
TracrRNA (Trans Activating crRNA)- a Nobel Prize-Winning Finding in CRISPR-Gene Editing Read More »
“PAM stands for Protospacer Adjacent Motif, which functions as two-factor authentication for Cas to cleave the foreign invading DNA only.” The CRISPR system has been an integral part of bacterial …
Importance of PAM Sequence (Protospacer Adjacent Motif) in CRISPR System Read More »
“CRISPR naturally has spacer sequences in-between and works in sync with the CAS protein as an adaptive immune system in bacterial and archaea.” The story of CRISPR and its fascinating …
How does the CRISPR-Mediated Adaptive Immune System Work in Bacteria? Read More »
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