CRISPR-CAS9 in the Treatment of Ataxia Type 2
“The Year 2020, was the grand time for Ataxia treatment based on the CRISPR-based technology. Three consecutive studies on Ataxia type 1, type 2 and type 3 proving the CRISPR …
CRISPR-CAS9
TracrRNA (Trans Activating crRNA)- a Nobel Prize-Winning Finding in CRISPR-Gene Editing
tracrRNA short for Trans-active crRNA binds with the crRNA and guides the CAS protein for effective DNA cleaving. “CRISPR-CAS9 system is an integral part of the bacterial immune system and …
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Importance of PAM Sequence (Protospacer Adjacent Motif) in CRISPR System
“PAM stands for Protospacer Adjacent Motif, which functions as two-factor authentication for Cas to cleave the foreign invading DNA only.” The CRISPR system has been an integral part of bacterial …
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How does the CRISPR-Mediated Adaptive Immune System Work in Bacteria?
“CRISPR naturally has spacer sequences in-between and works in sync with the CAS protein as an adaptive immune system in bacterial and archaea.” The story of CRISPR and its fascinating …
How does the CRISPR-Mediated Adaptive Immune System Work in Bacteria? Read More »
What is CIRSPRa or CRISPR activation?
CRISPRi or CRISPR activation is a process to upregulate gene expression or activate genes by effector activators, dcas9 and sgRNA. In 2021, CRISPR have deep penetration in diverse scientific fields. …
What is CRISPRi or CRISPR interference?
CRISPRi, short for CRISPR interference, is designed to repress gene expression using the customized sgRNA and dCAS. CRISPR- CAS9 is simply amazing! Why? Because it can edit a gene at …
