“Loss of Heterozygosity (LOH) is defined as the absence of one normal parental allele or gene (or part of the chromosome) in an organism which usually results in cancer.“ Like […]
What is Loss of Heterozygosity? How It is Associated with Cancer? Read More »
“Somatic mutations occur in somatic cells and can’t be inherited whilst the germline mutations occur in germ cells and inherited onto offspring.” 3 somatic mutations are reported per healthy individual
What is Somatic and Germline Mutation? Read More »
“The MTHFR gene encodes an enzyme known as methylenetetrahydrofolate reductase that breaks down homocysteine amino acid. C677T and A1298C are two common mutations of the MTHFR gene.” Enzymes are proteins
Genetics of MTHFR: Gene, Mutations, Variants, Inheritance and Testing Read More »
“Various phenotypes and variations in different organisms are evolved due to the mechanism known as genetic polymorphism.” DNA is known to us only since 1950, ‘chemically’ explained in 1953 by
Role of Genetic Polymorphism in Human Evolution and Survival Read More »
“Genetic disorders occur due to alterations in either gene, DNA or chromosome which can cause serious health or medical problems.” Genetic disorders are congenital, commonly, however not in all cases.
100 Common Genetic Disorders Read More »
“Mutagen is a physical, chemical or biological agent that causes mutation by altering the genetic material which possibly results in the disease condition.” In a simple language, we can say
Mutagen: Definition, Types and Effect Read More »
