“Loss of Heterozygosity (LOH) is defined as the absence of one normal parental allele or gene (or part of the chromosome) in an organism which usually results in cancer.“ Like …
What is Loss of Heterozygosity? How It is Associated with Cancer? Read More »
“Somatic mutations occur in somatic cells and can’t be inherited whilst the germline mutations occur in germ cells and inherited onto offspring.” 3 somatic mutations are reported per healthy individual …
“The MTHFR gene encodes an enzyme known as methylenetetrahydrofolate reductase that breaks down homocysteine amino acid. C677T and A1298C are two common mutations of the MTHFR gene.” Enzymes are proteins …
Genetics of MTHFR: Gene, Mutations, Variants, Inheritance and Testing Read More »
“Various phenotypes and variations in different organisms are evolved due to the mechanism known as genetic polymorphism.” DNA is known to us only since 1950, ‘chemically’ explained in 1953 by …
Role of Genetic Polymorphism in Human Evolution and Survival Read More »
“Genetic disorders occur due to alterations in either gene, DNA or chromosome which can cause serious health or medical problems.” Genetic disorders are congenital, commonly, however not in all cases. …
“Mutagen is a physical, chemical or biological agent that causes mutation by altering the genetic material which possibly results in the disease condition.” In a simple language, we can say …
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