What is a Sonic Hedgehog (SHH) gene?
Sonic Hedgehog (SHH) gene forms the sonic hedgehog protein having a pivotal function in embryonic morphogenesis. Yesterday night I was watching a TV show on Sony BBC earth (the copyright
Maternal Cell Contamination In Prenatal Genetic Testing
“Maternal cell contamination is defined as the presence of maternal cells in a fetal sample such as amniotic fluid or chorionic villi. It creates preanalytical problems during testing.” Prenatal genetic
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What is a Palindromic DNA Sequence?
“A sequence when read from 5’ to 3’ and 3’ to 5’ direction on two antiparallel strands shows sequence similarity is said as the palindromic DNA sequence.” Our genome, in
What is Gel Shift Assay or EMSA?
EMSA stands for Electrophoretic Mobility Shift Assay often known as gel shift assay is a technique to study the nucleic acid and protein interaction. The present technique is used ‘in
What is DNA footprinting?- Principle, Steps, Process and Applications
“DNA footprinting studies the DNA sequence protein interaction thereby transcriptional activities in vitro within or outside the cell.“ Transcription is a complex biological process whose final product is obviously a
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Cas9 Protein: Structure, Function, Types and Importance
“The Cas9 protein is a nuclease that destroys phage DNA using the double RNA-guided DNA cleavage through DNA binding and nuclease activities.” Key points: Cas9 protein is predominantly present in
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