“The Cas9 protein is a nuclease that destroys phage DNA using the double RNA-guided DNA cleavage through DNA binding and nuclease activities.” Key points: Cas9 protein is predominantly present in […]
Cas9 Protein: Structure, Function, Types and Importance Read More »
“CRISPR works magically in every sense! Every time scientists doubt something and do research, they get more than that, something new and amazing. Yet, it’s not so complex.” Do you
How does the CRISPR CAS9 System Distinguish Self vs Nonself DNA?- 7 Proven mechanisms Read More »
“The Year 2020, was the grand time for Ataxia treatment based on the CRISPR-based technology. Three consecutive studies on Ataxia type 1, type 2 and type 3 proving the CRISPR
CRISPR-CAS9 in the Treatment of Ataxia Type 2 Read More »
tracrRNA short for Trans-active crRNA binds with the crRNA and guides the CAS protein for effective DNA cleaving. “CRISPR-CAS9 system is an integral part of the bacterial immune system and
TracrRNA (Trans Activating crRNA)- a Nobel Prize-Winning Finding in CRISPR-Gene Editing Read More »
“PAM stands for Protospacer Adjacent Motif, which functions as two-factor authentication for Cas to cleave the foreign invading DNA only.” The CRISPR system has been an integral part of bacterial
Importance of PAM Sequence (Protospacer Adjacent Motif) in CRISPR System Read More »
“CRISPR naturally has spacer sequences in-between and works in sync with the CAS protein as an adaptive immune system in bacterial and archaea.” The story of CRISPR and its fascinating
How does the CRISPR-Mediated Adaptive Immune System Work in Bacteria? Read More »
