What is Somatic and Germline Mutation?
“Somatic mutations occur in somatic cells and can’t be inherited whilst the germline mutations occur in germ cells and inherited onto offspring.” 3 somatic mutations are reported per healthy individual […]
What is the Function of RNase?
“RNase- acronym as ribonuclease is the class of nuclease used to inhibit the activity of the RNA during DNA extraction. Two types of ribonucleases are endoribonuclease and exoribonuclease.” Interesting information:
What is the Ct value of SARS-CoV-2 (COVID-19) RT-PCR?
“A Higher Ct value indicates a lower viral load whilst the lower Ct value indicates a higher amount of viral load in the sample.” I went twice for RT-PCR in
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How to Increase DNA Purity and Yield?
“A pure & good quality DNA has a 260/280 ratio between 1.7 to 1.8 and a yield between 100ng/µL to 300ng/µL is used for PCR, DNA sequencing and other downstream
What is DNase?- Definition, Structure, Function and Types
“DNase is the group of DNA enzymes and a type of nuclease used for hydrolytic cleaving of the DNA. It has lucrative applications in biological science and therefore has great
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The Concept of ChIP-Seq (ChIP-Sequencing) Explained
“Sequence information of DNA linked with associated proteins like histones can be obtained by performing high throughput DNA sequencing, such technique is known as ChIP-Seq.” Highlights: ChIP-seq was developed by
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