Optimizing PCR Cycles to Get Good Results
Usually, 25 to 35 cycles a typical PCR reaction needs to get a good amount of amplification, containing denaturation, annealing and extension simultaneously at 95ºC, 50 to 68ºC and 72ºC. […]
Genetics
What is Post-Translational Modifications (PTMs)?- 10 Most Commonly Studied PTMs
“Post-translational modifications, abbreviated s PTMs are the biological modifications that occur after protein synthesis which alters protein structure and function. Common PTMs are phosphorylation, Methylation, acetylation, lipidation, hydroxylation and ubiquitination.
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How DNA “Proofreading” Occurs During Replication?- 4 Ways It Happens
Replication is a process to manufacture a new DNA, a duplex DNA makes another duplex. DNA polymerase actively participates in this process and controls the whole from start to end.
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What is Genetic Predisposition?-Definition, Mechanism and Test
“The science behind the probability of getting certain kinds of disease or finding the likelihood of getting, it is said as genetic predisposition.” For the past couple of weeks, I
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What is Somatic and Germline Mutation?
“Somatic mutations occur in somatic cells and can’t be inherited whilst the germline mutations occur in germ cells and inherited onto offspring.” 3 somatic mutations are reported per healthy individual
What is the Function of RNase?
“RNase- acronym as ribonuclease is the class of nuclease used to inhibit the activity of the RNA during DNA extraction. Two types of ribonucleases are endoribonuclease and exoribonuclease.” Interesting information: